Corneal transplantation (penetrating keratoplasty) is frequently used to restore vision in patients with corneal opacities caused by disease or trauma. However, in certain cases, standard transplants may not be successful, especially in patients with:
Repeated immunologic transplant rejection
End-stage dry eye diseases (e.g., Stevens-Johnson syndrome)
Severe chemical burns
In such cases, keratoprosthesis (KPro) becomes a viable alternative. The Boston KPro, the most widely used artificial cornea globally, is implanted in place of the diseased, opaque cornea. Acting as a clear window in the center of the eye, KPro differs from natural tissue in that it does not become opaque or vascularized—making it less prone to complications commonly seen in traditional transplants.
This has made KPro a preferred option in cases of previous graft failures and tissue degeneration. Its use represents a major advancement in modern medicine, offering hope to millions of people suffering from corneal blindness.
